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Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile

Figure 2

Melanization of G. mellonella infected with C. krusei.

(A) Visual appearance of G. mellonella larvae infected with different C. krusei doses. (B, C and D) Optical Density (OD) of the haemolymph of G. mellonella infected with C. krusei ATCC 6258 (B), clinical isolate CL8053 (C) and CL80317 (D) with 5×105, 106, 5×106 cells/larva. The different size inoculum reveals dose-response melanization (* p<0.05). All the experiments in this figure were performed at 37°C.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0060047.g002