Excisional Wound Healing Is Delayed in a Murine Model of Chronic Kidney Disease
Figure 6
Chronic kidney disease demonstrated significantly less cellular proliferation in the early stages of wound healing.
Representative immunofluorescent sections of wound edges stained with BrdU and DAPI in A) normal mice and B) chronic kidney disease mice at day 7. C) Utilizing Tissue Gnostics quantification technology, chronic kidney disease wounds demonstrated significantly less cellular proliferation in the early stages of wound healing. (Arrows indicate wound edges, white dots indicate epidermis, and brackets indicate dermis) (* p<0.05, ** p<0.01) (Magnification ×200) (n = 6–8 mice/group).