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Excisional Wound Healing Is Delayed in a Murine Model of Chronic Kidney Disease

Figure 2

Mice exhibited different degrees of chronic kidney disease.

A) By controlling the amount of cautery to the injured kidney, moderate and severe degrees of chronic kidney disease were produced. Only mice with a severe degree of chronic kidney disease were wounded for experimental purposes. (n = 6–8 mice/group) B) These animals exhibited metabolic derangements analogous to those in human chronic kidney disease and a notable growth retardation.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0059979.g002