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The Paratenon Contributes to Scleraxis-Expressing Cells during Patellar Tendon Healing

Figure 5

Gene expression of tenogenic transcription factors and fibril assembly proteins were reduced in the defects.

Scx, Mkx, Tnmd, Dcn, and Fmod were all decreased in defects compared to contralateral shams and normal PT. (A) Principal component 1 (PC1) scores (along bottom axis) for treatment groups and loadings for genes of interest (along top axis) show genes that were up-regulated (point to left) and down-regulated (point to the right) in the defects. (B) Scatterplots depicting improved correlations with normal PT over time (horizontally) and changes in expression between the defects and shams (vertically).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0059944.g005