2,2′-Diphenyl-3,3′-Diindolylmethane: A Potent Compound Induces Apoptosis in Breast Cancer Cells by Inhibiting EGFR Pathway
Figure 1
Anti-proliferative effects of indole derivatives.
(A), Schematic diagrams of indole and its derivatives used in this study. (B), Broad-spectrum anti-proliferative effects of indole derivatives were measured in various cancer cell lines such as DBT-RG-05MG, MCF7, MDA-MB 231, MDA-MB 468, DU145, HCT116, as well as in HEK293. Cells were exposed to the compounds for 72 hr before MTT assay. The bars represent the percent (%) cell viability and standard deviation (SD) obtained from four independent experiments.