Cytotoxic Activity and Apoptosis-Inducing Potential of Di-spiropyrrolidino and Di-spiropyrrolizidino Oxindole Andrographolide Derivatives
Figure 5
Study of cell cycle arrest in HCT116 cells by propidium iodide.
Percentage of G0–G1 cell population increases after treatment of 20 µM of CY2 and andrographolide for 24 h and 36 h, indicating G1/S phase cell cycle arrest.