γ-Tocotrienol Induces Paraptosis-Like Cell Death in Human Colon Carcinoma SW620 Cells
Figure 4
Morphological changes of paraptosis-like cell death were observed in SW620 cells by transmission electron microscopy (TEM).
After treatment with 15 (B), 30 (C), 45 (D) and 60 µmol/L (E) of γ-tocotrienol for 24 h, SW620 cells showed the swelling of mitochondria or ER (red arrowheads) and extensive cytosolic vacuolization (red arrows). The micrographs (A) provided normal cells control. The significant swellings of mitochondria or ER were observed after treated with 60 µmol/L of γ-tocotrienol for 6 h (F).