Gene Expression Profile Analysis of Type 2 Diabetic Mouse Liver
Figure 5
An overview of the key fatty acid and glucose metabolic gene nodes and their alteration in the 9-week-old diabetic db/db mouse liver.
The gene nodes and their interactions were obtained from literatures, and the alteration of gene expression was from Table S1. Orange arrows indicate the metabolic flux of glucose and fatty acid. Purple arrows indicate the interaction between different metabolic processes and the indicated signaling pathway. Red arrows show that the indicated process and pathway are expected to be upregulated in diabetic mouse liver based on the detected mRNA levels. Red and gray circles labeled on each gene indicate the genes are upregulated and unaffected in diabetic mouse liver respectively. CD36, fatty acid translocase; GLUT2, glucose transporter 2.