Gene Expression Profile Analysis of Type 2 Diabetic Mouse Liver
Figure 2
Genes and the related biological processes altered in diabetic mouse liver.
(A) The 8551 selected genes as described in Figure S1A were separated into two distinct clusters according to the genes upregulated or downregulated in diabetic (DB) mouse liver compared with normal (N) control. Red lines indicate Cluster A including 1933 upregulated genes in diabetic mouse liver. Blue lines indicate Cluster B including 694 downregulated genes . Purple lines indicate the total 2627 altered genes, which include all genes in Cluster A and B. (B) The clustered genes were assigned to different biological processes based on Gene Ontology using the web tool DAVID. The top 10 biological functions and the case genes in each cluster ranked by P-value were listed (case genes ≥ 10).