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Cell Volume Regulation in Cultured Human Retinal Müller Cells Is Associated with Changes in Transmembrane Potential

Figure 6

Modeling of cells exposed to different extracellular media compositions.

Time courses of Vt/V0 (A), Vm/Vm0 (B), Jnet (C) and Vm, EqCl, EqK (D) simulated in cells exposed to either HYPONaCl or to HYPOMannitol. At time = 0 extracellular osmolarity was reduced (ΔOsM = 100 mOsM) and after a delay of 20 s, PK and PCl increased according to Equation 4. A negative value of Jnet indicates an outward flux.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0057268.g006