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Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection

Table 6

A direct comparison in terms of the Areas Under the Curve (AUC) and oral doses associated with a 99% reduction of cfu counts in the lungs of infected mice (ED99) compared to untreated control for rifampicin, isoniazid, moxifloxacin and compound 9.

Table 6

doi: https://doi.org/10.1371/journal.pone.0056980.t006