Differential MicroRNA Regulation Correlates with Alternative Polyadenylation Pattern between Breast Cancer and Normal Cells
Figure 5
Correlation between target site abundance of up-regulated microRNAs and LSR change in MCF-7 cells.
Box plots for log2 ratios of (A) LSR, (B) long-isoform expression, and (C) short-isoform expression change between MCF-7 and MCF-10A cells against target-site abundance of MCF-7-up-regulated microRNAs in aUTRs. The genes with more target sites encounter a greater LSR decrease and long-isoform expression decline in MCF-7 cells. However, differential expression of the short isoform shows little correlation with target site abundance.