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Conformational Effects on the Circular Dichroism of Human Carbonic Anhydrase II: A Multilevel Computational Study

Figure 3

Calculated and experimental near-UV CD spectra of all tryptophan mutants of HCAII.

The experimental spectra are shown in black, the predicted spectra with the matrix method based on single structure are shown in blue; the predicted spectra with the matrix method based on the MD snapshots are shown in red; TDDFT calculations are shown in green.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0056874.g003