Biochemical Characterization of Uracil Phosphoribosyltransferase from Mycobacterium tuberculosis
Figure 7
Evaluation of nucleotides as allosteric effectors.
All reactions contained 350 µM PRPP and 35 µM uracil. (•) standard reaction, (○) standard reaction containing 500 µM GTP, (□) standard reaction containing 500 µM CTP, (Δ) standard reaction containing 500 µM ATP, (×) standard reaction containing 500 µM UTP, (▪) standard reaction containing 100 µM UMP, (▴) standard reaction containing both 100 µM UMP and 500 µM CTP.