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Morphology-Based Prediction of Osteogenic Differentiation Potential of Human Mesenchymal Stem Cells

Figure 5

Schematic illustration of two scenarios examined to simulate clinical feasibility.

A: (Scenario I) New patient prediction scheme: Trained by historical patient dataset only. Images from all passages of patient 3 were used for prediction. B: (Scenario II) Ongoing patient prediction scheme: Trained by historical patient datasets and a partial dataset from the new patient. For example, for the prediction of cell potential of patient 3, Scheme I uses images of patient 1 and 2 only. Scheme II used images of patient 1 and 2, together with some images from patient 3.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0055082.g005