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Adaptation to Experimental Jet-Lag in R6/2 Mice despite Circadian Dysrhythmia

Figure 5

Representative double plotted actograms from mice undergoing phase-advance and phase-delay.

WT (A, B) and R6/2 (C, D) mice were exposed to either phase-advance (A and C) or phase-delay (B and D). Shaded regions represent dark phase of LD cycle. Lines were drawn to plot onsets of activity for each mouse (as shown for representative mice in A-D). Lines from all mice are shown superimposed in E and F.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0055036.g005