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Metabolomic Profiles Delineate Signature Metabolic Shifts during Estrogen Deficiency-Induced Bone Loss in Rat by GC-TOF/MS

Figure 5

PLS-DA score plots of plasma samples.

(A) PLS-DA score plots of OVX rats and sham rats at the 12^th weeks post-surgery; (B) PLS-DA score plots of OVX rats and sham rats at the 24^th weeks post-surgery; (C) PLS-DA score plots of OVX rats between the 12^th weeks and 24^th week post surgery. Letters M and S denotes the OVX group and the Sham group, respectively. Numbers 12 and 24 represents different time points during the experiment: 12, week 12; 24, week 24.

doi: https://doi.org/10.1371/journal.pone.0054965.g005