Metabolomic Profiles Delineate Signature Metabolic Shifts during Estrogen Deficiency-Induced Bone Loss in Rat by GC-TOF/MS
Figure 3
PLS-DA score plots and 3D plots.
Partial least squares projection to latent structures and discriminant analysis (PLS-DA) score plots (A: PC1/PC2) and 3D plots (B: PC1/PC2/PC3) of the OVX group over the process of bone loss. X-axis, Y-axis and Z- axis were labeled with PC1 (the first principal component), PC2 (the second principal component), PC3 (the third principal component) respectively. Letters M denotes the OVX group. Numbers 0–12 represents different time points during the experiment: 0, before experiment; 3, week 3; 6, week 6 et al. M3 means the point from the sample in the OVX group at the 3rd week after the experiment. One data point stands for one subject: for instance, M3 and M6 mean the point from the sample in the OVX control rats at the 3rd and 6th week after surgery.