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Neurotrophic and Neuroprotective Actions of (−)- and (+)-Phenserine, Candidate Drugs for Alzheimer’s Disease

Figure 5

Enhanced doublecortin reactivity in the SVZ of 4–6 months old APPswe mice after (+)-phenserine treatment.

Doublecortin (DCX) immunoreactivity in the subventricular zone (SVZ) in 4–6 months old mice are shown in A and B. Cortical BDNF levels in wt 4–6 months old mice are shown in C. **p<0.01 compared to wt mice treated with saline. Results are expressed as mean ± SEM.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0054887.g005