Circulating MicroRNA-150 Serum Levels Predict Survival in Patients with Critical Illness and Sepsis
Figure 2
Serum miR-150 levels of critically ill patients at ICU admission.
(A) Serum miR-150 levels at admission to the intensive care unit were analyzed by qPCR and revealed a trend toward reduced miR-150 concentrations in critically ill patients (n = 223) as compared with healthy controls (n = 76). (B) Serum miR-150 concentrations at admission to the ICU were not significantly changed in critically ill patients with high initial Acute Physiology and Chronic Health Evaluation (APACHE) II scores (>10) in comparison to patients with low APACHE-II-scores (</ = 10). Box plot are displayed, where the bold line indicates the median per group, the box represents 50% of the values, and horizontal lines show minimum and maximum values of the calculated non-outlier values; asterisks and open circles indicate outlier values.