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Stat3 Inhibitor Stattic Exhibits Potent Antitumor Activity and Induces Chemo- and Radio-Sensitivity in Nasopharyngeal Carcinoma

Figure 2

Stattic inhibits Stat3 activation in a dose- and time-dependent manner in NPC cells.

NPC cell lines were treated with and without Stattic at the specified concentrations for 2 h (A) or exposed to 20 µM Stattic for different time points (B). Expression of T-Stat3, p-Stat3, cyclin D1, and β-actin were examined by western blot. DMSO were used as control in “0” groups.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0054565.g002