Fear Learning Increases the Number of Polyribosomes Associated with Excitatory and Inhibitory Synapses in the Barrel Cortex
Figure 5
A. Excitatory synapses located on spines containing polyribosomes have larger postsynaptic density area than those on spines without polyribosomes (two-way ANOVA, p<0.0001) and the synapses enlarge during conditioning (ANOVA, p<0.01). Synapses on spines without polyribosomes do not significantly differ in size in the control, in the conditioned group (CS+UCS) and in the pseudoconditioned group (PSEUDO). Graph shows means ± SD (*p<0.05, *p<0.01, ***p<0.001). B. Inhibitory synapses located on spines containing polyribosomes have larger postsynaptic density area of than those located on spines without polyribosomes (two-way ANOVA, p<0.0001) and the synapses enlarge during conditioning (ANOVA, p<0.05). Synapses on spines without polyribosomes do not significantly differ in size in the control, in the conditioned group (CS+UCS) and in the pseudoconditioned group (PSEUDO).