Crucial Roles of the Protein Kinases MK2 and MK3 in a Mouse Model of Glomerulonephritis
Figure 2
Survival rate of mice with disrupted MK2 and/or MK3 genes following injection with AMC serum.
13 mice from each group were given 100 µl of either control serum or AMC serum by i.v. injections for 4 consecutive days (days 1–4). At day 8, one or two mice from each group with pronounced disease symptoms were sacrificed for tissue harvesting (open arrow). These mice were included in the mortality count. At day 16, one or two mice from each group with no obvious disease symptoms were also sacrificed (closed arrow). These mice were excluded from the mortality count. *Log rank test.