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A Computational Model to Predict Rat Ovarian Steroid Secretion from In Vitro Experiments with Endocrine Disruptors

Figure 2

Overview of the compartments used to model in vitro (A) or in vivo (B) hormone transports.

In vitro (A), the exterior compartment corresponds to the culture medium. In vivo (B), the ovary tissue is subdivided into three compartments: granulosa cells, “other cells” for thecal and interstitial cells, and extracellular space.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0053891.g002