Long-Term In Vivo Imaging of Fibrillar Tau in the Retina of P301S Transgenic Mice
Figure 5
Ex vivo analysis of FSB-positive cells.
A, B FSB-positive cells were counted in retinal whole mounts of P301S mice (red, AT8; white, FSB; green, YFP). C Quantification of FSB-positive cells of homozygous and heterozygous P301S mice in cohorts of different ages (n = 5–6). Each data point represents the number of FSB-positive cells in one retina normalized to the area. Shown are mean values ± SD. **P<0.01; ***P<0.001. D, E AT8-staining in the cortex of homozygous P301S mice at the age of 2 and 5 months. Scale bars: 1 mm (A), 100 µm (B, D, E).