Oculomotor Deficits in Aryl Hydrocarbon Receptor Null Mouse
Figure 5
The AhR is expressed in the eyes during the development of AhR+/+ mice.
In situ hybridization is performed on coronal sections of the mice eyes at two embryonic stages (E12 and E14) with digoxigenin-labeled riboprobes for AhR. (A & C) E12 coronal section of AhR+/+ (A) and AhR−/− mice (C); no expression of AhR is detected at this stage. (B & D) E14 coronal section of AhR+/+ (B) and AhR−/− mice (D); the black arrow (in B) indicates the expression of AhR in the retinal ganglion cells. Scale bar represent 250 µm.