All-Trans Retinoic Acid in Combination with Primaquine Clears Pneumocystis Infection
Figure 5
No relapse of PcP after cessation of ATRA-PMQ treatment.
Immunosuppressed, Pc-infected mice were treated with ATRA-PMQ or TMP-SMX for 2 weeks and then examined for the presence of Pc at 3 weeks after initiation of treatment and at 3 weeks after cessation of the three-week treatment. Lung tissues were subjected to Pc mitochondrial rRNA PCR, and the PCR products were electrophoresed on a 1% agarose gel.