Normal T Cell Selection Occurs in CD205-Deficient Thymic Microenvironments
Figure 5
CD205-deficiency does not impact upon TCRVβ distribution in a polyclonal T cell repertoire.
Flow cytometric analysis of TCRVβ distribution in adult Ly75−/− and Ly75+/− littermates for (A) CD4+8− (SP4) thymocytes, (B) CD4−8+ (SP8) thymocytes, (C) CD4+8− splenocytes, and (D) CD4−8+ splenocytes. Error bars show ± standard error for 3 independent experiments. Statistical analysis performed using Mann Whitney U test, no significant (n.s.) differences were determined between TCRVβ usage in Ly75−/− and Ly75+/− mice.