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Investigate Pathogenic Mechanism of TXNDC5 in Rheumatoid Arthritis

Figure 6

Cell proliferation and cell invasion in RASFs (n = 15) treated with CoCl2 and TXNDC5-siRNA.

(A) The cell viability of RASFs was determined using an MTT assay. (B) The invasive ability of RASFs was examined using a 2-compartment transwell system. The average number of cells that invaded through the filter was quantified. (C) Crystal violet staining of the lower surface filters revealed the cells that passed through the filter and attached to the lower side of the filter (100×). The data were obtained from three independent experiments. * = p<0.05, ** p<0.01, *** = p<0.001.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0053301.g006