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Pathway Analysis Reveals Common Pro-Survival Mechanisms of Metyrapone and Carbenoxolone after Traumatic Brain Injury

Figure 5

Metyrapone and carbenoxolone attenuate gene expression in both pro-survival and pro-death pathways.

(A) Axon guidance signaling pathway is associated with regeneration and growth. (B) TNFR1 signaling pathway is associated with inflammation and cell death. (See Fig. S15 for symbol key).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0053230.g005