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Genomic Analysis of Melioribacter roseus, Facultatively Anaerobic Organotrophic Bacterium Representing a Novel Deep Lineage within Bacteriodetes/Chlorobi Group

Figure 5

An overview of the metabolism of M. roseus.

Enzymes and proteins identified in the genome are in blue, energy-rich intermediate compounds are in red. Enzyme abbreviations: HK, hexokinase; PGI, phosphoglucose isomerase; PFK, phosphofructokinase; FBA, fructose-bisphosphate aldolase; TIM, triose phosphate isomerase; GPDH, glyceraldehyde 3-phosphate dehydrogenase; PGK, phosphoglycerate kinase; PGM, phosphoglycerate mutase; PYK, pyruvate kinase; LDH, lactate dehydrogenase; PDH, pyruvate dehydrogenase; POR, pyruvate ferredoxin oxidoreductase; ACS, acetyl-CoA synthetase; Pyc, pyruvate carboxylase; Mae, malic enzyme; Pck, phosphoenolpyruvate carboxykinase; GltA, citrate synthase; Acn, aconitase; Icd, isocitrate dehydrogenase; Oor, 2-oxoglutarate ferredoxin oxidoreductase; Fum, fumarase; Mdh, malate dehydrogenase; SDH, succinate dehydrogenase; Tkt, transketolase; TalB, transaldolase; ACIII, alternative complex III; COX, cytochrome c oxidase; ArsC, arsenite reductase; NAD(P) trans HDR, NAD(P) transhydrogenase; Nos, nitrous oxide reductase; PPase, pyrophosphatase. Other abbreviations: GAP, glyceraldehyde-3-phosphate; 3-PG, 3-phosphoglycerate; 2-PG, 2-phosphoglycerate; L-Ru-5-P, L-ribulose-5-phosphate; D-Ru-5-P, D-ribulose-5-phosphate; Fdox/Fdred, ferredoxin, oxidized and reduced form; Cyt, cytochrome; Pi, phosphate; PPi, pyrophosphate; CoA, coenzyme A.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0053047.g005