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Necrosis Is the Dominant Cell Death Pathway in Uropathogenic Escherichia coli Elicited Epididymo-Orchitis and Is Responsible for Damage of Rat Testis

Figure 5

RNA expression pattern of the bcl-2 family genes in the testis.

The expression of the anti-apoptotic gene bcl-2 (A), pro-apoptotic genes bax (B), bid (C), bim (D) and bak (E) in the testis were determined with quantitative real time PCR. Target gene expression levels were normalized with the endogenous control ß-2-microglobulin (ß2M). Data are present as 2ΔCt, ΔCt = Cttarget gene-Ctß2M. The Mann-Whitney U test was employed for statistical analysis (* p<0.05). Each single symbol (circle and triangle) represents one individual testis sample.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0052919.g005