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CD-NP: A Novel Engineered Dual Guanylyl Cyclase Activator with Anti-Fibrotic Actions in the Heart

Figure 5

LV Fibrosis.

Representative histology images at 10x objective magnification of the LV stained with picrosirius red (upper panels) and the quantification of LV fibrosis staining (lower graph) in Sham+Vehicle, UNX+Vehicle and UNX+CD-NP rats. Values are mean ± SEM. *P<0.05 vs Sham+Vehicle and P<0.05 vs UNX+Vehicle.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0052422.g005