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A Unified Model of the GABAA Receptor Comprising Agonist and Benzodiazepine Binding Sites

Figure 5

Agonist binding modes determined by induced fit docking.

A) GABA (green), B) THIP (pink) and C) muscimol (cyan) are shown in the orthosteric binding site at the interface between the β2 subunit (teal) and the α1 subunit (smudge).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0052323.g005