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Deletion of Chromosomes 13q and 14q Is a Common Feature of Tumors with BRCA2 Mutations

Figure 5

Cumulative rates of gain and loss for tumors analyzed by CGH (red, 4 BRCA2-mutant tumors; black, 24 BRCAX tumors).

A, All chromosomes; B, Chromosome 13; C, Chromosome 14. Each vertical line in B & C corresponds to an individual BAC probe. When the red line reaches −1, all of the tumors showed loss for that probe.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0052079.g005