Delayed Contrast Extravasation MRI for Depicting Tumor and Non-Tumoral Tissues in Primary and Metastatic Brain Tumors
Figure 5
Examples of vessel morphology sampled from regions appearing blue in the maps of patients with primary brain tumors are shown in images A–F. Vessels from regions appearing red in the maps are shown in G–I. Samples D and G were taken from patient #4. Samples B, E, H and I were taken from patient #1. A and C were taken from patient #11 and F was taken from patient #13. It can be seen that the samples obtained from blue regions in the maps (A–F) present swollen endothelial cells, dilated lumen, peri-vascular dense fibrous tissue and glomeruloid lumen. Samples taken from red regions in the maps show different stages of vessel necrosis. The vessels shown in G show early necrosis, with scattered blood cells surrounding the necrotic vessels, while the vessels in H and I show later stages of vessel necrosis. The silhouette is reserved and there are residual red blood cells but the endothelial cells are necrotic.