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Rimmed Vacuoles in Becker Muscular Dystrophy Have Similar Features with Inclusion Myopathies

Figure 1

Pathological Characteristics of BMD patients. A:

On mGT staining, RVs are seen in the periphery of myofibers (arrow). B: On H&E staining, there is marked variation in fiber size with scattered small atrophic fibers. C: High acid phosphatase activity is seen in the areas of RVs. D: On ATPase staining pre-incubated at pH 4.6, RVs are seen in both type 1 and type 2 fibers. Asterisks indicate myofibers with RVs. Scale bar: 25 µm.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0052002.g001