Enterovirus 71-Induced Neurological Disorders in Young Gerbils, Meriones unguiculatus: Development and Application of a Neurological Disease Model
Figure 2
21-day-old gerbil infected IP with ten-fold serial dilution of EV71.
Control animals were given uninfected Vero cell lysate. Survival (A) and clinical scores (B) were monitored daily after inoculation. Clinical scores were defined as following: 0,healthy; 1,ruffled hair, hunchbacked or reduced mobility; 2,limb weakness; 3,paralysis in 1 limb; 4,paralysis in both limbs; 5,death. Each group contained seven or eight gerbils. One representative of two independent experiments was shown.