Energy Efficient Neural Stimulation: Coupling Circuit Design and Membrane Biophysics
Figure 5
Fixed versus adjustable compliance voltage.
(A) Stimulator energy consumed to maximally activate a rat sciatic nerve. Stimulator set to a compliance voltage of 5 V, 10 V, 20 V and the minimum compliance voltage. Stimulation tested across a range of pulse-widths. Incomplete datasets (compliance voltage was insufficient to activate nerve in some animals) were not included in statistical analyses. (B) For reference only, the stimulator energy consumed to activate rat sciatic nerve, with incomplete datasets included. (C) Energy consumed by the FET and by the load across a range of pulse-widths, with compliance voltage minimized. Error bars represent standard error.