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Genome-Wide Transcriptome and Proteome Analysis on Different Developmental Stages of Cordyceps militaris

Figure 5

Differentially expressed genes associated with putative cordycepin metabolic pathway at different developmental stages.

(A) Putative cordycepin metabolic pathway derived from purine metabolic pathway. Red boxes represent some genes in the steps are up-regulated in mycelium, while green boxes represent that in fruiting body. Black boxes mean the common expression level of genes in the steps between mycelium and fruiting body. The detailed information of genes involved in the pathway was listed in Table 3. (B) Validation of the gene expression in cordycepin metabolic pathway by quantitative RT-PCR. Actin gene CCM_03787 was the reference. The expression levels of randomly selected genes in fruiting body were set as control samples and those in mycelium were normalized to the control. The values are the results of three technical repetitions (mean ± SD).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0051853.g005