DREAM Mediated Regulation of GCM1 in the Human Placental Trophoblast
Figure 5
Changes in DREAM expression modified GCM1 levels in BeWo cells.
(A) DREAM silencing of BeWo cells increased GCM1 mRNA levels. (B) DREAM over-expression in BeWo cells reduced GCM1 mRNA levels. Data presented as mean+\−SEM from 4 independent experiments with each value determined in triplicate. Each treated time point was compared to an equivalent non-silenced time point control. All non-silenced control time points are set as 1. *** p<0.001, * p<0.05. NS, non-silenced.