Cryopreserved Dental Pulp Tissues of Exfoliated Deciduous Teeth Is a Feasible Stem Cell Resource for Regenerative Medicine
Figure 5
SHED transplantation suppresses circulating and local levels of Th17 cells in MRL/lpr mice.
(A, B) Flow cytometry of peripheral CD4+IL17+IFNgamma− Th17 cells. (C) Serum levels of IL-17. (D) Homing of systemically infused CFSE-labeled SHED-Cryo and SHED-Fresh to lymph node (LN) and kidney of MRL/lpr Mice after 1- (Day 1), 2- (Day 2) or 7- (Day 7) day transplantation. Dot-circled area: glomerular. (E) ELISA of IL-17 an IL-6 levels in lymph node and kidney. A–E: n = 5 for all group. MRL/lpr: control group, SHED-Cryo: SHED-Cryo-transplant group, SHED-Fresh: SHED-Fresh-transplant group. B, C, E: *P<0.05, **P<0.01, ***P<0.005, ns: no significance. The graph bars represent mean±SD.