Advancing Optical Imaging for Breast Margin Assessment: An Analysis of Excisional Time, Cautery, and Patent Blue Dye on Underlying Sources of Contrast
Figure 5
Average percent errors for Monte Carlo simulated data and phantom data.
Data is shown for a single reference “phantom” (<µa> = 3.85 cm−1, <µs’> = 6.79 cm−1 for the simulated data; <µa> = 3.02 cm−1, <µs’> = 5.81 cm−1 for the phantom data). Simulated: 216 diffuse reflectance spectra were created consisting of 3 levels of scattering (4.85, 6.68, 9.15 cm−1), THb (16.97, 31.03, 55.09 µM), and β-carotene (10.29, 16.29, 24.37 µM) and 8 levels of patent blue dye (0∶10:70 µM). Phantom: patent blue dye was titrated 12 times (0–79 µM) into a phantom consisting of 5.81 cm−1 (<µs’>), 16.69 µM (THb), and 11.23 µM (β-carotene).