MHC Class II-Restricted Presentation of the Major House Dust Mite Allergen Der p 1 Is GILT-Dependent: Implications for Allergic Asthma
Figure 5
Gilt−/− lymphocytes exhibit deficient recall proliferation to the cockroach allergen Bla g 2 but not to the house dust mite allergen Der f 1.
Recall proliferation analysis of lymphocytes isolated from (A) Bla g 2- or (B) Der f 1-challenged mice and incubated with increasing concentrations of purified (A) Bla g 2 or (B) Der f 1. Data shown as mean ± SEM of triplicate wells and are representative of two independent experiments; * p<0.05, ** p<0.001.