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Methylselenol Formed by Spontaneous Methylation of Selenide Is a Superior Selenium Substrate to the Thioredoxin and Glutaredoxin Systems

Figure 7

Effect of selenium compounds on superoxide production.

H157 cells were stained with hydroethidine and treated for 5 h with selenite (5 µM) +/− SAM (500 µM), and MSA (5 µM) before detection of accumulated superoxide produced by FACS analysis, as described under materials and methods.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0050727.g007