Elongation Factor 1 alpha1 and Genes Associated with Usher Syndromes Are Downstream Targets of GBX2
Figure 2
Bioinformatic analysis of the top 286 GBX2 target genes.
(A) Tissue expression analysis for the top 286 genes targeted by GBX2 determined by DAVID. Of the top 286 genes targeted by GBX2, 51% are expressed in the nervous system: 38% brain, 1% brain stem, 2% brain cortex, 3% hippocampus, 7% fetal brain. (B) The top two GBX2 DNA-binding consensus motifs bioinformatically determined by Motif Sampler analysis of GBX2 ChIP-Seq target sequence fragments.