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Beta-Lapachone, a Modulator of NAD Metabolism, Prevents Health Declines in Aged Mice

Figure 6

βL shifts expression patterns towards those for calorie restriction.

(A) Parametric analysis of gene-set enrichment (PAGE) (up-regulated (red) or down-regulated (blue)) (B)(upper) Venn diagram shows number of overlapping genes between data sets.(lower) Gene ontology analysis. Results are plotted as negative log-transformed p- values.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0047122.g006