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Spermine Attenuates the Action of the DNA Intercalator, Actinomycin D, on DNA Binding and the Inhibition of Transcription and DNA Replication

Table 1

Numerical values of the SPR-derived association rate constants, dissociation rate constants, and association equilibrium constants (ka, kd, and Ka) for immobilized hairpin DNA upon binding to ACTD in the presence of various concentrations of spermine.

Table 1

doi: https://doi.org/10.1371/journal.pone.0047101.t001