The Amygdala as a Neurobiological Target for Ghrelin in Rats: Neuroanatomical, Electrophysiological and Behavioral Evidence
Figure 5
Effects of intra-amygdala administration of ghrelin or a ghrelin antagonist (JMV2959) on cumulative food intake.
Normal chow intake was measured at 1, 2, 4, and 24 hr following unilateral intra-amygdala injection of either (A) ghrelin (0.3 and 1 µg) to freely-fed rats or (B) JMV2959 (2 or 10 µg) to overnight fasted rats. Data are expressed as mean ± S.E.M. *P<0.05 **P<0.01 ***P<0.001, vs. saline. Paired sample t-test, SPSS.