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Mechanistic Insights into Validoxylamine A 7'-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex

Figure 2

An Sequence Alignment of VldE and OtsA.

Shown is the protein sequence alignment of VldE and OtsA as generated by ClustalW2 [54]. Residues whose side-chains are involved in ligand binding are indicated with shaded boxes. Conserved residues are indicated with unfilled boxes. The two-dimensional secondary structure of VldE and OtsA are also illustrated next to the corresponding sequence with α-helixes represented by spirals and β-strands represented by arrows. Numerical values for helices and strands are assigned.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0044934.g002